Non-specific symptoms pathway (2024)

Key learning from wave 2

This material is based on our 5 ACE Projects which became the focus of our Wave 2 activity. Here you can find the key learning and documents to date.

This paper published in the BJC summarises our first results from the MDC projects. Diagnosing cancer in patients with non-specific symptoms with an 8% conversion rate and demonstrating the diagnostic potential of a dedicated referral pathway for non-site specific symptoms.
First results from five multidisciplinary diagnostic centre (MDC) projects

This summary report highlights the key findings from the five MDC projects and draws together the learning gained from their implementation. It also includes an overview of data from the evaluation period.
Key Messages from the evaluation of the MDCs

This material is based on feedback from the projects and covers: timing, essentials to developing MDC plans, working with primary care, key data elements and operational challenges.
ACE Programme early learning leaflet

This document outlines the key findings from the qualitative evaluation carried out by the Policy Research Unit for Cancer Awareness, Screening and Early Diagnosis on behalf of ACE.
Qualitative Evaluation Summary
Full Report

How MDCs can improve early diagnosis

The Multidisciplinary Diagnostic Centre (MDC) concept is similar to arrangements in Denmark where a patient can undergo several diagnostic tests in one location, often on the same day, leading to a faster diagnosis.

An MDC doesn’t have to be a new ‘centre’. Instead, it can be set up within an existing hospital or community setting and would supplement cancer specific diagnostic pathways.

MDCs can potentially be an effective way to support patients with non-specific symptoms who tend to present late, and to support GPs whom are often unsure of the appropriate referral pathway for non-specific symptomatic patients.

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Non-specific symptoms pathway (1)

DownloadMDC infographic

Our animated video looks at the benefits of the MDC pathway from 6 different perspectives. It features the views of ACE team members who are assessing the effectiveness of the MDCs and clinicians who are working on the pathway, supporting patients with non-specific but concerning symptoms

Watchour video -Features of the ACE MDC pathway

Developing knowledge about rapid referral pathways for non-specific symptoms

The documents below have been created to develop knowledge of the MDC model for non-specific symptoms.

The distinguishing features paper provides a descriptive overview of project approaches to the MDC model within the five projects:

Distinguishing features of the MDC model

The design principles document identifies three models, as well as a set of overarching MDC design principles

MDC models and principles

This article addresses the challenges associated with achieving a full and rigorous evaluation of MDC cost effectiveness, before describing some of the practical approaches employed at a project level to understand pathway cost.

Project approaches to understanding pathway cost

The following article may be of interest to local commissioners and policy makers interested in implementing MDC-based pathways in their areas
An approach to building the local case for the MDC

This document lists the data items to be collected as part of the MDC evaluation. A full list is available upon request.

Wave 2 projects

Airedale Wharfedale and Craven
The MDC pathway was designed for patients presenting with non-specific symptoms who need diagnosis and treatment or referral within a few days of presentation but do not necessarily require hospital admission.

Greater Manchester
The two MDC sites trialled a same-day ‘hot-reporting’ diagnostic service model, including provision for individualised health risks assessments, personalised behavioural change interventions, and health promotion services.

Leeds
The project was based on a virtual MDC concept within shared hospital diagnostic resources, with a primary aim to ‘improve patient experience and outcomes by getting the quickest, most accurate diagnosis for people with non-specific, concerning symptoms with GP suspicion of cancer’

London Cancer
The project piloted the MDC concept across five sites, including urban specialist and urban district general settings. The overarching aim of the project was to improve access to diagnostics, patient survival, experience and costs associated with cancer presenting with non-specific but concerning symptoms.

Oxfordshire
The pathway accepted patients aged 40 years and older (a population of approximately 345,000) for whole-body, low dose, contrast enhanced CT and broad panel of laboratory investigations as the first tests for all referrals. The overarching aim of the project was to improve the time to referral for testing and diagnosis for patients with non-organ specific symptoms who do not meet the national 2WW referral criteria.

Vague symptoms projects cluster (wave 1)

These documents summarise our learnings from the ACE Vague Symptoms cluster in Wave 1, a series of projects aimed to explore ways of achieving earlier diagnosis of cancer for patients that are currently not served well by existing referral guidelines, processes and pathways. The pilots took place across August 2014 – March 2018.

Please see the Executive summary and Full Report from this cluster.

Executive summary Full report

A list of other documents available upon request

Non-specific symptoms pathway (2024)

FAQs

Non-specific symptoms pathway? ›

The non-specific symptoms (NSS) pathway provides a route for patients presenting with vague symptoms who may have a serious illness.

What are non-specific symptoms? ›

What are non-specific symptoms?
  • Unexplained weight loss.
  • Vague abdominal pain.
  • Nausea/appetite loss.
  • Fatigue.

What is the 2ww non-specific pathway? ›

This pathway is designed to give GPs a quick and efficient way to access this full group of tests for patients with “non - specific” symptoms. Patients of the UHNM NHS Trust who are referred can expect rapid diagnostic scans, (Computed Tomography or CT), possibly blood tests and if not completed by your GP a poo test.

What does it mean if symptoms are non-specific? ›

Non-specific is a widely-used term in radiology, and clinical medicine in general. Non-specific is used for a symptom, sign, test result, radiological finding, etc., that does not point towards a specific diagnosis or etiology.

What is the symptom pathway? ›

The vague symptom pathway (VSP) is a fast-track clinic that GPs can refer patients to for investigations to rule out cancer. Before you attend your GP will arrange for some blood tests to be taken so that when you come to the clinic, the VSP team have enough information to make a thorough assessment.

What is an NSS pathway? ›

The non-specific symptoms (NSS) pathway provides a route for patients presenting with vague symptoms who may have a serious illness.

What are non-specific health symptoms? ›

Nonspecific symptoms, sometimes also called equivocal symptoms, are not specific to a particular condition. They include unexplained weight loss, headache, pain, fatigue, loss of appetite, night sweats, and malaise.

What does 2WW mean in medical terms? ›

The Two-Week Wait appointment system was introduced so that anyone with symptoms that might indicate cancer could be seen by a specialist as quickly as possible. Attending this appointment within two weeks is vitally important and will allow you to benefit from: Early reassurance that cancer has not been diagnosed or.

What is a 2 week urgent pathway? ›

Early diagnosis of a disease may mean more effective treatment and better outcomes. For this reason, where there is a possibility that symptoms could indicate cancer, people are referred urgently to see a specialist (on what is called a 'two-week pathway').

What is the green pathway pregnancy? ›

The green pathway is a defined pathway of care for women with no medical or obstetric problems, and with an uncomplicated pregnancy.

What is meant by nonspecific? ›

adjective. ˌnän-spi-ˈsi-fik. Definition of nonspecific. as in general. relating to the main elements and not to specific details his criticism of the picture is fairly nonspecific, but he clearly doesn't like it.

What is a nonspecific finding on a CT scan? ›

These findings are not specific. Often, they do not mean there is cancer. For example, a CT scan of a lung finds a tiny, benign (not cancer) nodule in about 2 out of every 3 people. It's often from scars from a past infection. We usually monitor these tiny or nonspecific lesions at follow-up exams.

What is the meaning of non specificity? ›

: lacking in detail or particulars. nonspecific answers. a nonspecific description. b. : not caused by a specific or identified agent.

What is a pathway disease? ›

Broadly, a disease pathway in the PPI network is a system of interacting proteins whose atypical activity collectively produces some disease phenotype. 3,4,12,16. Given the PPI network .

What is a diagnosis pathway? ›

A diagnostic pathway is the route that patients take from first presenting their symptoms to a clinician to receiving their diagnosis.

What is a clinical pathway example? ›

Primary Objective: • Identifies what the pathway's intended outcome is • Includes which patients and/or what areas the pathway will be used For example: Develop a pathway for treating asthma that directs patient care from the Emergency Department through inpatient management to discharge.

What does the medical term non-specific mean? ›

A non-specific disease or condition does not result from any one particular cause: Chest pain is a non-specific symptom that can have cardiac or no cardiac causes.

What is nonspecific condition? ›

A “nonspecific symptom” is something that is reported by a patient but cannot be observed. Nonspecific symptoms may include chronic fatigue or pain that is not related to a known injury. For all its complexity, the body has only so many ways to show injury and so many ways to combat disease.

What are non-specific symptoms of inflammation? ›

Some of the common signs and symptoms that develop during chronic inflammation are listed below.
  • Body pain, arthralgia, myalgia.
  • Chronic fatigue and insomnia.
  • Depression, anxiety and mood disorders.
  • Gastrointestinal complications like constipation, diarrhea, and acid reflux.
  • Weight gain or weight loss.
  • Frequent infections.

What are non-specific infections? ›

Nonspecific infection involves harm to the body through the invasion of unknown microorganisms.

References

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